Microbiology Essay Example | Topics and Well Written Essays - 500 words

Microbiology - Essay Example These findings established an association between the â€Å"questioning† microbes and disease. Indicating that disease is caused due to the attack by tiny micro-organisms. This formed the basis for further research. Whereas, Robert Koch in 1890, physician and bacteriologist further, confirmed this microbial association with the disease. Based on his constant research he established that: a. The bacteria must be present in every disease. b. The bacteria must be isolated from the host suffering from the disease and should be grown in the pure culture. c. The disease must be repeated and reproduced if organism from the pure culture is inoculated into a healthy host. d. Again the same bacteria should be revered from the infected host. All these systematic postulation were not laid by Bassi and Pasteur. Although these postulates do not work when there is no animal model available to test a specific bacteria. Moreover a few bacteria cannot be grown in pure culture in the laboratory conditions, e.g. Mycobacterium laprae the causal organism of leprosy cannot be grown in pure culture. In certain cases virulence or disease causing ability is acquired, so the postulate does not hold true. In certain cases the microbe gains access via trauma, injury or through surgery, then also Koch's postulate are not valid.